Study Set Content:
fusing two cells to produce a hybridoma
Monoclonal antibodies (mAb)
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the produced Ab is called m
mAb
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is the first FDA approved monoclonal antibody drug.
Muromomab (OKT3
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Muromonab (OKT3
murine
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Muromonab (OKT3 antibody against T-lymphocyte
CD3
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reverses acute kidney transplant
rejection
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Antigen
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Spleen cells (polyclonal antibodies)
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Myeloma cells
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Fuse and form hybridoma
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Selecting cells making desired antibody(monoclonal antibody)
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-omab
murine
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-ximab –
chimeric
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-zumab –
Humanized
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-umab –
fully human
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-omab – murine (ex.
Muromomab
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-ximab – chimeric (ex.
Infliximab
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-umab – fully human (ex.
Adalimumab
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-zumab – humanized (ex
Omalizumab
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first gene therapy drug
Gendicine
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Study Set Content:
fusing two cells to produce a hybridoma
FLASHCARD
the produced Ab is called m
FLASHCARD
is the first FDA approved monoclonal ant...
FLASHCARD
Muromonab (OKT3
FLASHCARD
Muromonab (OKT3 antibody against T-lymph...
FLASHCARD
reverses acute kidney transplant
FLASHCARD
Item 87
FLASHCARD
Item 88
FLASHCARD
Item 89
FLASHCARD
Item 90
FLASHCARD
Item 91
FLASHCARD
-omab
FLASHCARD
-ximab –
FLASHCARD
-zumab –
FLASHCARD
-umab –
FLASHCARD
-omab – murine (ex.
FLASHCARD
-ximab – chimeric (ex.
FLASHCARD
-umab – fully human (ex.
FLASHCARD
-zumab – humanized (ex
FLASHCARD
first gene therapy drug
FLASHCARD
