Advantages of Capsules & Tablets
conveniently carried, readily identified, and easily taken
Gives (blank) to the prescriber and (blank) individualized dosage to
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flexibility,accurate
(blank) and (blank) manufactured
efficiently and productively
shipped by manufacturers at (blank) and with less (blank)
lower cost, breakage
more(blank) and have a longer (blank) than their liquid counterparts.
stable, shelf-life
a solid DF where medicinal agents and/or inert
substances are enclosed in a small shell of
gelatin
Capsule
produced from partial hydrolysis of collagen obtained from the
skin, white connective tissue, and bones of animals
Gelatin
is gelatin soluble?
insoluble
but it soften in cold water by absorbing water up to
10x its weight
it is soluble in
hot water and in warm gastric fluid.
It is digested by
proteolytic enzymes and absorbed.
is derived from acid-cured tissue
Type A gelatin
is derived from alkali-cured tissue
Type B gelatin
who has better storage stability
Type A
In addition, gels prepared with high(blank) exhibited
improved storage stability compared to low
Bloom strength gelatins
Hard gelatin shell
gelatin sugar and water
Soft gelatin shell
gelatin, glycerin or a polyhydric alcohol such as sorbitol
contains 13% to 16% of moisture
Hard gelatin
Hard gelatin, High humidity
distorted and lose shape
Hard gelatin, low humidity
brittle and crumble