Which acids are used in the preparation of collodion?
A. Hydrochloric acid and nitric acid
B. Hydrochloric acid and sulfuric acid
C. Sulfuric acid and nitric acid
D. Sulfuric acid and acetic acid
pyroxylin, nitrocellulose, soluble gun cotton, collodion cotton
Collodion
Obtained by the action of a mixture of sulfuric and nitric acids (1:1) on cotton (consists chiefly of cellulose tetranitrate)
Collodions
Clear or slightly opalescent viscous liquid prepared by dissolving pyroxylin (4% w/v) in a 3:1 mixture of ether and alcohol
Collodions
Useful in holding the edges of an incised wound together, but uncomfortable because of its inflexible nature
Collodions
Highly volatile and flammable
Collodions
collodions are applied to the skin with a fine
camel’s hair brush or glass applicator
Flexible Collodion
2% - waterproofing
Camphor
3% - flexibility or plasticity
Castor oil
10% salicylic acid in flexible collodion
Salicylic acid collodion
Keratolytic
Salicylic acid Collodions
One drop at a time application, line the healthy skin with white petrolatum to avoid irritation
Salicylic acid collodion
solvent or solvent mixture
Menstruum
is the most versatile and most used, with inherent preservative power and prevents separation of extractives upon standing
Hydroalcoholic
can be a co-solvent of water and alcohol
Glycerin
plant residue after actives are removed
Marc
What are the two main methods for extraction?
Process M
Process P
Process M
Maceration
comminuted drug is allowed to soften, penetrated by the menstruum
“soak”
MACERATION deg.C for 3 days
15C – 20