-(when used as intended), contra-indication to the use of the medicine in relation to drugs or conditions, mismatching between patient and medicine, omitted medicine/ingredient, patient allergic to treatment wrong/omitted/passed expiry date, wrong/omitted patient information leaflet, wrong/omitted verbal patient directions/ wrong/ transposed/ omitted medicine label, wrong/unclear dose or strength. Wrong drug/ medicine, wrong formulation, wrong frequency, wrong method of preparation/ supply, wrong quantity, wrong route, wrong storage