Study Set Content:
location, facilities, seasonal time and temperature
Patient’s environment
Each sulfa drug is prescribed to reduce the quantity since the combination is (blank), and the total dose is reasonable.
additive
The initial dose is intended to bring an
immediate effect
The antibacterial spectrum and therapeutic uses of sulfonamide mixtures are the same as those of the individual components but an advantage of such mixture is the lesser incidence of (blank) associated with their use.
crystalluria and renal injury
The usual adult dose of Phenobarbital is
30 mg
The usual adult dose of Phenobarbital is 30 mg, but single doses of (blank) are prescribed occasionally.
100 mg
However, high doses of Phenobarbital should not be taken frequently because it has a (blank) duration of action.
long-term
Factors To Be Considered In Judging The Danger Or Safety Of A Dos
- The frequency of dose/administration
- Dosage form in which administered
- Age, weight or Patient’s BSA
- Sex of the patient
Severity and type of illness
Over the past years, various rules for calculating infant and child dosages have been devised. are sometimes more (blank) than adults to certain Drugs.
susceptible
Doses for infants and children, where they are known, may be found in the
USP, and APhA booklet
Doses for infants and children, where they are known, may be found in the USP, and APhA booklet entitled
Pediatric Dosage Handbook and textbooks on the pediatrics.
Doses should be calculated when it is possible to obtain the actual
infant’s or child’s dose
Relates the surface area of individuals to dose. It is thought that this is a more realistic way of relating dosages
The square meter square surface area method
The average body surface area for an adult has been given as
1.73 m2
If there is need to determine a patient's BSA, a (blank)
nomogram
Many drugs have doses stated as the amount of drug/m2 body surface area and may be calculated as follows
Drug/m2 x BSA in m2= Individual’s dose
Many physiological functions are proportional to BSA as
metabolic rate and kidney function
This is the most common way of determining children's doses.
Mg/kg x body weight= Individual’s dose
Drug doses also may be stated in units, as with
vitamins A and D, penicillin, and hormones.
This means that a certain quantity of biological activity of that drug is called
1 unit
