- Tubes must be stoppered during centrifugation to avoid aerosol contamination and leaks during the process.

- The tube stopper must be covered with absorbent materials such as gauze to prevent spraying of the specimen.

- Availability and use of cell counting instruments that has the ability to pierce the tube stopper during sampling to prevent the need on opening the tube during analysis is highly recommended.

- The use of face shield or googles or any clear Plexiglas shield between laboratorian and blood sample being manipulated is highly recommended.