is the major extracellular cation
Sodium
is the major intracellular cation
Potassium
If cation pumps are not working, it will increase in intracellular monovalent cations and water and it begins to swell (increase sodium inside) causing osmotic hemolysis.
sea urchin appearance
kissing lips or coffee bean shaped
Both statements are correct:
- If free floating, the RBC will decrease in size
- If the proteins detach, the RBC will wiggle
Alpha and Beta chain connects with another dimer forming
heterodimer
RBCs are produced through normablastic proliferation and mature in bone marrow
cytoplasm of RBC contains calcium who has four globin chains
how many hours does the cytoplasmic ribosome and mitochondria of RBC disappears after it is released in bone marrow
24-48 hrs
without aerobic respiration, ATP is produced through Anaerobic glycolysis called
Embden-meyerhof pathway (EMP)
what are the reusable components of EMP
globin chains and iron from hemoglobin, phospholipids and proteins from cell membrane
what are the unreusable components
protoporphyrin ring of hemoglobin (excreted as bilirubin)
commonly disorder which makes RBC short
hereditary nonspherocytic hemolytic anemia
what do you call the 3 alternate pathway except EMP
diversions or shunts
when iron state is ferric, the affected hemoglobin molecule is called
methemoglobin
reduction of methemoglobin
methemoglobin reductase
everything you should know about RBC
mean volume 90fL
7-8um in size
140um surface area
can stretch if undamaged up to 2.5 times its resting diameter
MSCH greater than 36% reduced the RBC lifespan
Only hydrophilic domain group of cholesterol
b hydroxyl group