Study Set Content:
Discovered albuminuria in 1964 by boiling urine
Frederik Dekkers
Wrote a book about “pisse prophets”, inspired the passing of the first medical licensure laws in England
Thomas Bryant
Developed the first method of quantitative urine microscopic examination
Thomas Addis
Introduced urinalysis as part of a doctor’s routine patient examination in 1827
Richard Bright
Discovered Bence-Jones proteins; Father of Clinical Chemistry
Henry Bence-Jones
Ultrafiltrate of Plasma
Urine Formation
Final urine contains what
excess solutes
Daily urine output
1200 mL
How many mL is being converted to 1200 mL
170,000 mL
Urine Composition
95% water and 5% solute
Organic Components of Urine includes:
Urea, Creatinine & Uric Acid
Primary Organic Component
Urea
Product of protein and amino acid metabolism
Urea
What is the toxic compound produced by protein and amino acid as a byproduct
Ammonia
Ammonia is converted into a non-toxic compound. What is this compound?
Urea
Product of Creatine metabolism
Creatinine
Amino acid used up by the body muscle cells. As creatine is metabolized by muscle cells, creatinine is produced as byproduct
Creatinine
Nucleic acid break down (purines)
Uric Acid
Purines that are degraded into uric acid
Adenine & Guanine
It tends to crystallize once in the blood
Uric Acid
