Liver Function Test
Test for enzymes that reflect damage to
hepatocytes
Aminnotransferases (ALT and AST):
AST
:
Liver, cardiac muscle, skeletal muscle, kidneys,
brain, pancreas, lungs, leucocytes, and RBC - (Normal
serum level)
ALT
: Liver - (Normal serum level)
Liver cell damage – increased permeability – increase
serum levels
BUT poor correlation b/w liver cell damage and level of
AST and ALT
Up to 300 U/L – non specific/ any type of liver disorder