Study Set Content:
Minute living things that are usually unable to be viewed with the naked eye.
Microorganism
microbiological concepts, processes and techniques that are applied to pharmaceutical operations.
Pharmaceutical Microbiology
Can be defined as the study of microorganisms that are pertinent to the production of antibiotics, enzymes, vitamins, vaccines, and other pharmaceutical products
Pharmaceutical Microbiology
Study of microorganism that are pertinent to the production of:
· Antibiotic
· Enzymes
· Vitamins
· Vaccines
Also incorporates the study of microorganism that cause:
· Pharmaceutical contaminations
· Degradation
· Deterioration
· Spoil of pharmaceutical raw materials
· Finished products
One of the key objectives of pharmaceutical microbiology is to (blank) of pharmaceutical products
ensure safety and efficacy
As pharmaceutical microbiology is crucial to the manufacture and production of drugs, biologics, and devices, it is important that people working in these industries have a (blank) in order to avoid any potentially costly and life-threatening failures and consequences.
strong understanding and in-depth knowledge of pharmaceutical microbiological principles, techniques, processes, and strategies
Two Basic Types of Cells
· Prokaryotic Cells
· Eukaryotic Cells
– building blocks of life; All living things are made up of one or more cells; Cells only come from other cells; cells are small.
Cells
reproduces by binary fission; do not have cell nucleus or any other organelles with membrane
Prokaryotes
the only membrane of prokaryotes
Plasma membrane
Region of cytoplasm where prokaryote’s genome (DNA) is located. It is usually singular, circular chromosome.
Nucleoid
small extra piece of chromosome or genetic material; not critical to everyday functions. 5-100 genes.
Plasmid
Can provide genetic information to promote:
Antibiotic resistance
Virulence factors
Promote conjugation
(molecules produced by pathogen that specifically influence host's function to allow the pathogen to thrive)
Virulence factors
(transfer of genetic material between bacteria through cell-to-cell contact)
Promote conjugation
also known as proto-plasm
Cytoplasm
Gel like matrix of water, enzymes, nutrients, wastes, and gases and contains cell structures
Cytoplasm
Bacteria’s way of storing nutrients
Granules
- Location of growth, metabolism, and replication
Cytoplasm
