Study Set Content:
Most abundant; 80% of the serum antibody found after bacterial and viral infections
IgG
Predominant Ig in secretions; defense mechanism
IgA
First immunoglobulin to appear; efficient in agglutinating erythrocytes or bacteria; ABO antibodies are of this type
IgM
Reagins; constitute 0.004% of the total serum Ig; binds to mast cells releasing histamine
IgE
Main function not determined; found on the surface of B lymphocytes; maybe involved in cell differentiation; role is an antigen receptor
IgD
Major Ig expressed on the surface of B cells
IgG, IgM
Found in low concentrations in the blood serum
IgA, IgDÂ , IgE
TYPES OF IMMUNITY
Natural (Innate) immunity
Acquired immunity
endowed at birth and retained because of an individuals constitution
Natural (Innate) immunity
developed in response to the introduction of antigenic substances into the body
Active immunity
recovery from infection
Naturally acquired active
administration of a vaccine or toxoid; stimulating the body to make their own antibodies therefore producing immunity
Artificially acquired active
eveloped by the introduction of preformed antibodies (not antigens) into the body; immunity is not selfdeveloped but is passed from one individual to another
Passive immunity
transmission of antibodies from mother to child
Naturally acquired passive:
injection of immunizing biologics containing preformed antibodies
Artificially acquired passive
Origin of serum antibodies
B Cell
Originate in the BM but depend on the thymus gland for differentiation
T Cell
Arise from the bone marrow of humans
B Cell
Humoral system of immunity
B Cell
Agents of cellular immunity
T Cell
