b. Decreased conduction velocity at the AV node
c. Increased automaticity of the atrial muscle
d. Decreased effective refractory period in purkinje
system/ventricles
e. Bigeminy can be induced by digoxin
13. Which of the following increases the risk of digoxin induced
arrhythmias?
a. Hyperkalaemia
b. Hypercalcaemia
c. Hypermagnesaemia
d. Hyperuricaemia
e. Hypernatraemia
14. Digoxin
a. Is poorly lipid soluble
b. Is extensively metabolized
c. Has a half life in the body of 40 hours
d. Has minimal GI toxicity
e. Is 80% bound to plasma proteins
15. Drugs which may increase digoxin effect include all of the following
EXCEPT
a. Amiodarone
b. Diltiazem
c. Frusemide
d. Quinidine
e. Antacids
16. Which of the following drugs has the smallest volume of distribution?
a. Chloroquine
b. Verapamil
c. Imipramine