Study Set Content:
The suspension should pour (blank) from its container.
readily and evenly
List down different classes of pharmaceutical suspensions.
Orally administered suspensions:
Externally applied suspension
Parenteral suspensions
antibiotics; contain 125 to 500mg/5ml of solid material; greater concentration in drops.
Oral suspensions
generally contain high concentrations of suspended material.
Antacid and Radiopaque suspensions
lotions for topical use are designed for dermatologic, cosmetic, and protective purpose.
Externally applied suspension
Concentration of dispersed phase may exceed
20%
Parenteral suspensions contain from (blank) of solid particles.
0.5% to 30%
supply insoluble substances.
Suspensions
It can be a pleasant vehicle for administering distasteful substances, provide a suitable form for the application of dermatologic materials to skin and mucous membrane, and for the parenteral administration of insoluble drugs
Suspensions
expresses the velocity of sedimentation.
Stoke’s law
What are the limitation of Stoke’s equation?
it cannot apply to dilute pharmaceutical suspensions containing less than about 2g of solids per 100ml of liquid.
The particles in dilute suspensions do not interfere with one another during (blank), and free settling occurs
sedimentation
Also in most pharmaceutical suspensions that contain dispersed particles in concentrations of 5%, 10% or higher, the particles would interfere with one another and they would exhibit hindered
settling.
A substance that has the property of onto the surface or interfaces of the system.
Surfactant
(surface active agent)
Surfactant
A boundary between any two immiscible phases.
Interface
Is the minimum amount of work required to create that interface
Interfacial free energy
Denotes an interface where one phase is a gas, usually air.
Surface
In general, surfactants are classified according to their (blank) in aqueous solution, as ionic or nonionic surfactants.
behavior
negative ion
(anion)
