Study Set Content:
Acetylcholinesterase
25,000
Penicillinase
2,000
Lactate dehydrogenase
1,000
Chymotrypsin
100
DNA polymerase I
15
Tryptophan synthetase
2
Lysozyme
0.5
This turnover number is one of the largest known.
carbonic anhydrase
Enzyme Location Everywhere
Lactate dehydrogenase (LDH)
Isoenzymes:
Lactate dehydrogenase (LDH)
Widely distributed
Aspartate transaminase (AST) Serum glutamic oxaloacetic transaminase (SGOT)
Liver, heart, skeletal muscle, kidneys, brain, erythrocytes
Aspartate transaminase (AST) Serum glutamic oxaloacetic transaminase (SGOT)
Everywhere but predominantly in liver
Alanine transaminase (ALT) Serum glutamic pyruvic transaminase (SGPT)
Greatest concentration in prostate
Alkaline phosphatase (ALP)
Specific isoenzymes in prostate, liver, bone, kidney, intestine and placenta
Alkaline phosphatase (ALP)
Acute/chronic tissue damage
Lactate dehydrogenase (LDH)
Degree of elevation can indicate extent of damage
Lactate dehydrogenase (LDH)
Myocardial infarction
Aspartate transaminase (AST) Serum glutamic oxaloacetic transaminase (SGOT)
Isoenzymes may help to localize this
Lactate dehydrogenase (LDH)
Liver disease, viral hepatitis, bile duct problems
Alanine transaminase (ALT) Serum glutamic pyruvic transaminase (SGPT)
