Study Set Content:
Petrolatum, USP ▪ a purified mixture of semisolid hydrocarbons obtained from petroleum.
Oleaginous bases/hydrocarbon bases
a purified mixture of semisolid hydrocarbons obtained from petroleum
Petrolatum, USP
▪ a purified mixture of semisolid hydrocarbons from petroleum that has been wholly or nearly decolorized.
White Petrolatum, USP
▪ ointment differs from yellow ointment by substitution of white wax (bleached and purified yellow wax) and white petrolatum in the formula.
White Ointment, USP
Absorption bases
E.g., Hydrophilic Petrolatum, USP and Lanolin, USP (Anhydrous lanolin)
E.g., Hydrophilic Ointment, USP
• Water-removable Bases
E.g., Polyethylene Glycol Ointment, NF
• Water-soluble Bases
are oil-in-water emulsions resembling creams. Because the external phase of the emulsion is aqueous, they are easily washed from skin and are often called waterwashable bases.
Water-removable Bases
do not contain oleaginous components. They are completely water washable and often referred to as greaseless.
Water-soluble Bases
pharmacist may mix the components using mortar and pestle, or a spatula may be used to rub the ingredients together on an ointment slab (a large glass or porcelain plate or pill tile).
. Incorporation
all or some of the components of an ointment are combined by being melted together and cooled with constant stirring until congealed.
Fusion
• Components not melted are added to the congealing mixture as it is being cooled and stirred.
. Fusion
HYDROPHILIC OINTMENT
Synonym
• Unguentum Hydrophilicum
• Pomada Hidrofila
HYDROPHILIC OINTMENT
Uses:
• Used as a water removable ointment (washable ointment) protectant.
Emulsifying agent
Sodium Lauryl Sulfate
Oleaginous base
Stearyl alcohol and white petrolatum
Antimicrobial preservatives
Methyl paraben and propyl paraben
What are the hard-fusible bodies present in the preparation?
Wax, spermaceti
What is the ointment base used in the experiment?
Water removable bases or oil-inwater (o/w) emulsion ointment bases.
are non-occlusive, can be diluted with water, water washable, nongreasy.
Hydrophilic preparation:
