solid colloidal particles that include both nanospheres and nanocapsules with a capacity to release drugs
Nanoparticles
Liquid core and polymeric membrane
Polymer matrix and polymeric membrane
Liquid core
Active substance in molecular state
Polymeric membrane
thyroid function
131I
kidney function (aka renogram)
131I orthoiodohippurate
Myocardial perfusion imaging (MPI)*
201Tl thallous chloride
– “gold standard” of MPI
99mTc
designed to deliver therapeutic doses of ionizing radiation to specific disease sites, such as cancerous tumors, with high specificity in the body
Radiopharmaceuticals
Thyroid disease
treated with sodium iodide, 131I
Polycythemia vera
- treated with sodium phosphate, 32P
involves the targeted delivery of radiation to tumor cells or to the tumor microenvironment
Radiopharmaceutical therapy (RPT
Gastric urease to diagnose H. pylori
14C urea
Hodgkin's Disease, lymphoma, and bronchogenic carcinoma, inflammatory lesions.
67Gallium citrate
For in vivo diagnostic imaging or radiolabeling
11Indium
Several, depends on the form (e.g. 123I evaluates thyroid function)
123,125,131Iodine*
Treats somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors
177Lutetium dotatate
Thyroid, Urinary bladder, nasolacrimal imaging
99Molybdenum/99mTechnetium
Treats castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease
223Radium dichloride
for relief of pain in patients with confirmed osteoblastic metastatic bone lesions
153Samarium lexidronam