Drug reservoir
Control membrane
adhesive layer
Protective peel strip
thin, flexible sheet of material, usually composed of a polymer material; in a rapid dissolving form absorbed directly into systemic circulation
Oral Thin Film
designed to adhere to the gum or inner cheek to provide a controlled and sustained release of drug (e.g. Testosterone) through the buccal mucosa
Mucoadhesive system
semisolid confection that is designed to be chewed, releasing the API into the saliva
Medicated gums
Rate-controlled release
Osmotic pump
used for contraception; the drug is contained in the polymeric matrix and is released upon contact with vaginal fluids
Intrauterine device (IUD)
Drug reservoir
Rate-controlling membrane
monofilament thread
A biomaterial which contains the drug in the core of the ring where it is released immediately and continuously
Vaginal ring
Occlusive to retain skin moisture and hydrate the site of application
Backing layer
Pressure sensitive nonirritating allow easy peel-off
Adhesive layer
Backing layer example
polypropylene, polyethylene, polyolefin
Adhesive layer example
Polybutyl acrylate
Drug-release membrane example
polyethylene
e.g. epinephrine injection for IM use emergency supportive therapy of allergic reactions (anaphylaxis
Autoinjection systems
sterile wafers that usually contain biodegradable polymers with the drug embedded
Wafer implants