Main examples of Disperse Systems
Suspensions
emulsions
Gels and magmas
Aerosols
Solid in liquid
Suspensions
Colloidal dispersions
Gels & Magmas
Liquid in liquid
Emulsions
Gas in gas
Aerosols
combination of 2 different states of matter
Disperse system
transfer of solids
vehicle:
dissolves/solubilizes solids
Solvent
Insoluble particles dispersed in a liquid vehicle
Suspensions
Immiscible liquid dispersed in another liquid
Emulsions
A good suspension will appear
Homogenous
A good emulsion will appear
Homogenous
Contains a suspending agent
Suspensions
Contains an emulsifying agent
Emulsions
Suspensions examples
CMC, Bentonite, xanthan gum
Suspending and Emulsifying agents aid in
homogeneity
Dispersions of insoluble solid materials, generally the drug, in a liquid medium.
SUSPENSIONS
The most important consideration in suspension formulation development is the interaction between the
solid particles and the liquid vehicle
Formulator concern: suspensions
decrease rate of settling
- easy resuspendability
Aluminum hydroxide side effect =
constipation