Study Set Content:
This represent one-eight (1/8) of an apothecary fluid ounce but is frequently interpreted as
one teaspoonful
This represent one-eight (1/8) of an apothecary fluid ounce but is frequently interpreted as one teaspoonful when the physician uses this designation in his instructions to the patient. When the following prescription is considered, the problem becomes
evident
29.57 mL=
1 fl.oz
1 fl.oz =
6 teaspoons
1 fluid dram =
1/8 fl. oz(apothecary)
1/8 fl. oz(apothecary) =
1 teaspoonful
It is important because usually infants and children generally (but not always) require a smaller dose than adults.
age
quantity recommended for oral administration.
Most of the average dose of drugs (USP/NF)
given in smaller quantities than those orally and are tolerated safely
Drugs administered by injection
in ointment or liniment form, absorption is general variable so no relationship to the oral dose can be stated.
Locally
quantity is twice the oral although there are exceptions.
Rectal
Usually hypodermic dose is considered
½ the oral dose
Usually hypodermic dose is considered ½ the oral dose and the intravenous dose is considerably
less
If the drug has a (blank), there should be little concern about the short intervals of time between doses. They can be given more frequently than those with prolonged actio
fleeting action
On the other hand,(blank) may show toxic manifestation even though individual dose appears to be safe if frequency of administration is often. There should be more possible a large number of doses over a short time.
potent drug with cumulative action
Example of cumulative drug
Nux vomica, digitalis, mercury and its compounds, and arsenica
determines frequency of administration.
The type of drug action
There are several factors that may require altered dosage of individual drugs. Examples: 1. (blank) may be given more frequently than those slowly eliminated or have prolonged action
Quick acting and rapidly eliminated drugs
may require altered dosage of individual drugs, lower in case of additive or synergistic combination, higher in case of antagonistic combination.
Combination of drugs
Combination of drugs may require altered dosage of individual drugs, lower in case of
additive or synergistic combination
