Study Set Content:
Stimulants laxative
aloe. Senna (senokot), bisacodyl (Dulcolax)
ubricates stool and retard water reabsorption from the stool.
Lubricant laxative
Lubricant laxative
Mineral oil
Side effects
aspiration and lipid pneumonitis
(should be taken orally in an () to avoid sides effects).
upright position
works by activating chloride channels to increase fluid secretion in the intestinal lumen. • Used for chronic constipation
CHLORIDE CHANNEL ACTIVATORS: LUBIPROSTONE
side effect
nausea
Opioid-like actions on the gut. They activate presynaptic opioid receptors in the ENS to inhibit acetylcholine release and decrease peristalsis
ANTI-DIARRHEALS ▪ LOPERAMIDE
Side effects
drowsiness, abnominal cramps, dizziness
act by absorbing intestinal toxins or microorganisms by coating or protecting the intestinal mucosa
ADSORBENTS:
ADSORBENTS:
: aluminum hydroxide and methylcellulose
MOA: act by blocking dopamine receptors
ANTI-EMETICS
PHENOTHIAZINE
prochlorperazine, promethazine
MOA: enhance the effects of 5-HT3 blockers
5-HT, receptor blockers
5-HT, receptor blockers
ondansetron
• used in combination with other agents • may involve blockers of prostaglandins • can cause insomnia and hyperglycemia in patients with diabetes
CORTICOSTEROIDS:
CORTICOSTEROIDS:
dexamethasone and methylprednisolone
It targets the neurokinin receptor in the brain and blocks the actions of the natural substance.
NK3 BLOCKERS: Aprepitant
