Approaches ethical problems by addressing basic ethical principles, rooted in society's common morality
Principlism
Involves different stakeholders in a real discourse, to reduce bias and improve the validity and applicability of the HTA
Interactive, participatory HTA approaches
Addresses the interaction between society and technology and emphasizes how to shape technology in the best ways to benefit people
Social shaping of technology
Aims at a coherent conclusion by a process of reflective mutual adjustment among general principles and particular judgements
Wide reflective equilibrium
Intended use
Kill or inhibit growth of bacteria that cause infectious diseases
Antibiotics
Treatment of HIV/AIDS
Antiretroviral therapy
Relieve pain, fever, inflammation
Aspirin
Weight loss in obese patients
Bariatric surgery
Visualizing structues and blood flow in the body in real time
Medical ultrasonography
Identify men with prostate cancer early enough to cure
Prostate cancer screening with PSA test
Cardiovascular disorders, especially hypertension
Sildenafil
Unintended USES
Return to risky sexual behaviors in some patient groups
ART
Overuse and improper use leading to multi-drug resistant bacterial strains
Antibiotics
Antiplatelet to prevent blood clots
Aspirin
Fetal sex selection
Medical ultrasonography
Cure or remission of type 2 diabetes in many of the obese patients
Bariatric surgery
Invasive testing, therapies, and adverse effects for men with slow-growing/ low-risk cases that will never cause symptoms
Prostate cancer screening with PSA test
Treat male sexual dysfunction
sildenafil
Prevalence of a disease
Random sample survey of relevant population
Identification of risk factors for a disease
Case control study (for rare outcome) or cohortstudy(for more common outcome)