Liver Function Tests
Test that measure biosynthetic function of the
Liver
Coagulation factors:
What
is
measured
Prothrombin
Time
(PT)
-
collectively measures II/V/VII/X
Biosynthesis of factors II/VII/IX/X depends on Vit. K
PT may be elevated in hepatitis, cirrhosis and disorders
that result in Vit. K deficiency (eg obstructive jaundice)
Markedly prolonged PT (>5 secs above control), not
corrected by Vit. K is a poor prognostic sign in acute
viral hepatitis and other acute and chronic liver diseases