With Endo’s interest and background, he searched for fungi that would block this enzyme. In 1973, Endo found a substance made by the mold Penicillium citrinum that was a potent inhibitor on the enzyme needed to make cholesterol; it was named compactin (mevastatin) With the collaboration of Akira Yamamoto, a physician treating patients with extremely high cholesterol due to a genetic defect, Endo prepared samples of his drug, and it was administered to an 18- year-old (blank)% effective