It belongs to the family of (blank) and has a structure similar to that of (blank)
xanthine alkaloids
purine
Caffeine C8H10N4O2 is a CNS
stimulant
of caffeine can elevate mood and increase alertness,
Low doses
can cause headache and dizziness.
high doses
Properties
• 7-methyltheophylline
• guaranine
• theine
• Bitter taste
• Solutions in water are neutral to litmus
• Odorless
Caffeine
Synthesis of Caffeine • Reaction between
dimethylurea and malonic acid.
• Theobromine is treated with
methyl iodide and sodium methoxide.
Uric acid is treated with
methyl iodide in an alkaline solution
Uric acid is treated with methyl iodide in an alkaline solution, it produces
1,3,7- trimethyluric acid.
On heating this further with
phosphoryl chloride (POCl3
On heating this further with phosphoryl chloride (POCl3), it produces
chlorocaffeine,
• On heating this further with phosphoryl chloride (POCl3), it produces chlorocaffeine, which forms caffeine on further reduction with
hydrogen iodide
Uric acid
1,3,7- trimethyluric acid.
Enolic
Chlorocaffeine
Caffeine
Caffeine process
Uric acid to 1,3,7- trimethyluric acid.to enolic to chlorocaffeine to caffeine
adenosine