handheld machines, bedside, rapid results
POCT
non urgent (2H)
culture & sensitivity test (3D minimum - 5D maximum)
Routine
not routinely done — highly specific (hormones)
Special test
Units of Measure
Dillution: 20 microL of serum added to 180microL of saline
20:200 or 1:10
Largest value minus the smallest value
Range
Most used measure of variation. represents the average distance from the center of data.
Standard Deviation
Calculation to show number of SD's value from the target mean. comparison of one lab from another
Standard Deviation Index
Allows laboratory to compare SDs with different units and reflects the SDs percentage.
Coefficient of variation
Quality Control
Types of proficiency and test categories
waived, moderate complexity, and high complexity
requires training
moderate complexity
doesn’t need training — rapid tests
waived
need to have results interpreted well
high complexity
Methods of evaluation
Reproducibility, Reliability, Specificity, And Sensitivity
• detect only the analyte of concern
• avoids false positive
Specificity
• detect the smallest concentration of a certain substance
• avoids false negative
Sensitivity
maintain both accuracy & precision
Reliability
similar/near results with other machines
Reproducibility
the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes
Clinical Chemistry