Study Set Content:
CATHARANTHUS FAMILY
Apocynaceae/periwinkle
available in ampoules, recommended for generalized Hodgkin’s disease, lymphocytic lymphoma, histiocytic lymphoma, mycosis fungoides, advanced testicular carcinoma, Kaposi’s sarcoma, choriocarcinoma, & breast cancer unresponsive to other therapies.
VINBLASTINE SULFATE
ecommended for the treatment of acute leukemia. - also used in combination therapy in Hodgkin’s disease, lymphosarcoma, reticulum cell sarcoma, rhabdomyosarcoma, neuroblastoma & Wilms’ tumor
VINCRISTINE SULFAT
A semisynthetic derivative of vinblastine, released in 1984 -Employed for patients who have become resistant to vincristine and vinblastine.
VINDESINE
1. VINBLASTINE SULFATE RX
Velban®
VINCRISTINE SULFATE
Oncovin®
VINDESINE Rx
Eldisine®
PHYSOSTIGMA ON.
Calabar bean, Ordeal bean
ERGOT ON.
rye ergot, secale cornutum
NUX VOMICA SN
Strychnos nuxvomica S. ignatii
PHYSOSTIGMA
Physostigma venenosum
ERGOT SCIENTIFIC NAME
• Claviceps purpurea • Secale cereal
NUX VOMICA FAMILY
Loganiaceae
PHYSOSTIGMA
Leguminosae
ERGOT
• Clavicipitaceae • Gramineae
POISONING PRODUCED BY EATING FOOD AFFECTED BY ERGOT, TYPICALLY RESULTING IN HEADACHE, VOMITING, DIARRHEA, AND GANGRENE OF THE FINGERS AND TOES
ERGOTISM/ST. ANTHONY’S FIRE
E- ergonovine (ergometrine)
WATER SOLUBLE
– ergotamine & ergotoxine group
WATER INSOLUBLE
– methylergonovine, dihydroergotamine, methysergide & LSD
Semisynthetic alkaloids
An oxytocic, produces much faster stimulation of the uterine muscles.
Ergonovine maleate or ergonometrine maleate
