It acts against devitalized tissues in purulent states
DEOXYRIBONUCLEASE
or DESOXYRIBONUCLEASE
SUTILAINS
• A substance containing proteolytic enzymes from the bacterium
Bacillus subtilis
Use:
Wound debridement
COLLAGENASE
• An enzyme preparation obtained from fermentative cultures o
Clostridium histolyticum
LASPARAGINASE
• An enzyme obtained from cultures of certain strains of
Escherichia coli
Use:
Induces hematologic & clinical remissions of short duration for children with acute leukemia.
Nitrogenous organic substances produced by and associated with living matter
PROTEINS
They occur both in plants and in animals
PROTEINS
Plants store proteins in the form of
aleurone grains
hydrolyze entirely into amino acids
Simple proteins
combinations of protein & a nonprotein group(prosthetic)
Conjugated proteins
are degradation products of proteins
Derived proteins
meat, fish, eggs
Animal source
cereal grains, ex: wheat, soybeans
Plant source
Obtained from the partial hydrolysis of collagen, derived from the skin, white connective tissue & bones of animals (cattle, sheep & hogs)
GELATIN
When dry, gelatin is stable in
air
but when moist or in solution, it is subject to
bacterial decomposition.
____in cold water, but swells & soften when immersed in cold water gradually absorbing from 5 to 10 times its weight of water
Insoluble
Use:
- Pharmaceutic aid: encapsulating agent, suspending agent, tablet binder & coating agent.
- Vehicle
- Manufacture of suppositories
- Topical protectant (in combination with zinc oxide)
- A nutrient & used for the commercial food products, & for bacteriologic culture
Constituents:
- Amino acids: alanine, arginine, aspartic acid, glycine, cysteine, cysteine, glutamic acid, histidine, hydroxyproline, isoleucine, lysine, methionine, phenyalanine, tyrosine, proline, valine, serine,threonine
- Gelatin is an incomplete nutritional protein beacause tryptophan is absent.
- Gelatinizing constituent: known as chondrin
- Adhesive substance: known as glutin