CLASSIFICATION OF GLYCOSIDES
• According to glycone part (presence of sugar)
• According to their therapeutic effects
• According to the type of their glycosidic bond
• According to the aglycone part
glucoside group, like in sennoside
Glucose
rhamnoside in frangulin
Rhamnose
digitoxide in digoxin
Digitoxose
glucorhamnoside and glucofrangulin
Glucose and Rhamnose
rhamnoglucoside in rutin
Rhamnose and Glucose
CHF and Cardiac Muscles stimulators
digitalis glycosides, ouabain, k-strophantin, scillaren A & B, convolloside
Laxative group of glycosides
sennoside A B C D, cascaroside A B, frangulin and glucograngulin, aloin and barbaloin
Local irritant group
sinigrin, sinalbin
Analgesics and antipyretics
salicin
Keeping elasticity of blood vessels
rutoside
Anti-inflammatory group
aloin, glycyrrihizin
in these glycosides the sugar linked directly to carbon atom of aglycone
C-GLYCOSIDES
Example:
aloin
in these glycosides, the sugar part is linked with alcoholic or phenolic hydroxyl or carboxyl group
O-GLYCOSIDES
Example:
amygdalin, indesine, arbutin, cardiac glycosides, anthraquinone glycosides like sennoside
in these glycosides the sugar linked with nitrogen atom of (-NH2, -NH) amino group of aglycone like in nucleosides
N-GLYCOSIDES
Example:
DNA, RNA
in these glycosides the sugar is attached to a sulfur atom or SH (thiol group) of the aglycone such as in sinigrin
S-GLYCOSIDES
ACCORDING TO THE AGLYCONE PART
• Alcoholic glycosides
• Aldehydic glycosides
• Anthraquinone glycosides
• Lactone glycosides
• Cardiac glycosides
• Cyanophore glycosides
• Flavonoid glycosides
• Saponin glycosides
• Isothiocyanate glycosides
• Phenolic glycosides