The aglycone part is steroidal
CARDIAC GLYCOSIDES
Occur as glycosides with sugars attached at the 3-position of the steroid nucleus Because of their action on the heart muscle, they are named
cardiac glycosides.
EXAMPLES
Digitalis, Strophantus, and Scilla
Steroidal in nature
CARDIAC GLYCOSIDES
CARDIAC GLYCOSIDE OTHER NAME
Cyclopentanoperhydrophenanthrene nucleus
Classes:
Cardenolide
Bufadienolide
From the dried leaf of Digitalis purpurea
Digitalis or foxglove
Family:
Scrophulariaceae
Constituents:
digitoxin, gitoxin, gitaloxin
Uses:
congestive heart failure, paroxysmal atrial tachycardia, and atrial fibrillation
is a chronic progressive condition that affects the pumping power of your heart muscles.
Congestive heart failure (CHF)
While often referred to simply as _____ CHF specifically refers to the stage in which fluid builds up around the heart and causes it to pump inefficiently.
“heart failure,”
is a type of arrhythmia, or irregular heartbeat.
Paroxysmal atrial tachycardia
means that the episode of arrhythmia begins and ends abruptly.
Paroxysmal
means that arrhythmia starts in the upper chambers of the heart (atria).
Atrial
means that the heart is beating abnormally.
Tachycardia
(also called AFib ir AF) is a quivering or irregular heartbeat (arrhythmia) that can lead to blood clots, stroke, heart failure and other heart-related complications.
Atrial fibrillation
DIGITALIS
Digitalis lanata or
Grecian foxglove
Constituents:
digoxin, desacetyllanatoside C glycosides derived from aglycones of the C & D series maybe obtained only from D. lanata
CONVALLARIA Or lily of the valley root, is the dried rhizome and roots of
Convallaria majalis