importance of isotonicity in
pharmacy
ensure solutions do
not damage tissue or produce pain
when administered.
are formulated to be isotonic to duplicate ophthalmic tears for the comfort of the patient
ophthalmic preparations
ophthalmic solutions are also what to reduce irritation
buffered
Injections that are not isotonic should be administered
slowly
are hypotonic and can have profound adverse effects
Intravenous infusions
Large volumes of hypertonic infusions can result to
hyperglycemia, osmotic diuresis, excessive loss of electrolytes
Timolol Brand name
Optamol
Sodium Chloride + benzalkonium chloride brand name
Muconase
Gentamycin brand name
Genticin
Naphazolone hydrochloride brand name
Vasocon regular
Timolol Dosage Forms
Drops (ophthalmic solution)
Sodium Chloride + benzalkonium chloride Dosage Forms
Nasal spray
Gentamycin Dosage Forms
Eye/ Ear drops
Naphazolone hydrochloride Dosage Forms
Eye drops
Timolol
Antiglaucoma
Sodium Chloride + benzalkonium chloride Therapeutic Category/ Use
Nasal Decongestant
Gentamycin
Anti-infectives
Naphazolone hydrochloride Therapeutic Category/ Use
Opthalmic Antihistamine
Normal Saline Solution Osmolality
308 mOsm/L
Dextrose 5% in water Osmolality
252 mOsm/L