Pharmacrystal
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a) Increased
b) Decreased
c) Not changed
5.7) 400 mg of a drug is administered to a patient and the drug is later measured in
plasma to be 1 µg/ml. What is the apparent volume of distribution (Vd)?
a) 0.04 L
b) 0.4 L
c) 4 L
d) 40 L
e) 400 L
5.8) Elderly patients often have ____ muscle mass and thus a(n) ____ Vd.
a) More; Increased
b) More; Decreased
c) Less; Increased
d) Less; Decreased
5.9) Patients with ascites or edema would have ____ Vd for hydrophilic drugs, such as
gentamicin.
a) Increased
b) Decreased
c) Unchanged