Study Set Content:
Drugs have to be () from their formulations prior to analysis
extracted
Large amounts or organic solvent waste are () which are expensive to dispose of.
generated
The combination of HPLC with monitoring by() provides an accurate, precise
and robust method for quantitative analysis of pharmaceutical products that is industry standard
method for this purpose.
UV/visible detection
Monitoring of the stability of pure drug substances and of drugs in formulations, with ()
of any degradation products.
quantitative
Measurement of drugs and their metabolites in
biological fluids.
Determination of () and () values of drugs and of drug protein binding
partition coefficients , pKa
ASSAY:
• Assay of adrenaline injection injection by chromatography with an anionic ion-pairing agent
• Assay of ascorbic acid by chromatography with a cationic ion-pairing agent and electrochemical
detection
• Assay of ascorbic acid by hydrophilic interaction chromatography
• Assay of hyaluronic acid by size-exclusion chromatography
