Study Set Content:
Cost friendly
CLASSICAL
Minute sample are needed for analysis
Instrumental
Good precisions
Instrumental
Time consuming
Classical
Poor sensitivity
Classical
High maintenance cost
Instrumental
Skills and highly trained personnel is needed
Instrumental
Poor specificity and selectivity
Classical
Skills and highly trained personnel is needed
Instrumental
Constant calibration and monitoring
Instrumental
widely-used quantitative analytical method
Titrimetric / Volumetric Method
involves the measurement of volume of a solution of known concentration which is used to determine the concentration of the analyte
Titrimetric / Volumetric Method
Titrimetric / Volumetric Method
- acid-base titration (neutralization)
- Complexation method
- Precipitation method
- Oxidation reduction method
- Are chemical process in which an acid (proton donor) reacts with a base (proton acceptor).
- The product is a salt and water.
- These most commonly used a pH indicator, a pH meter to determine an end point.
- Neutralization reactions (acid-base reactions)
The direct or residual titrimetric analysis of acid using accurately measured volume of base.
Acidimetry
The direct or residual titrimetric analysis of base using accurately measured volume of an acid.
Alkalimetry
- Are based in the formation of complex between the analyte and the titrant
- EDTA is a chelating agent commonly used to titrate metal ions in solutions
- These titrations require special types of indicators that forms weaker complexes with the analyte.
Complexometric titrations / complexation
When a metal ion combines with a molecule which can donate electrons the resulting compound is called a
Complex
If the combining molecule contains two or more groups of that donates electron it is called a
CHELATE.
s a hexadentate ligand, which means that it binds six times. It binds twice at the nitrogens and four at the oxygens.
EDTA
