Study Set Content:
protection against developing alcoholism but it will increase the risk of acetaldehyde related cancer
Hyperventilation upon consumption -
acetaldehyde related cancer:
■ Esophageal ■ Stomach ■ Colon
Ethanol Toxic dose
: 0.7g/kg of pure ethano
which will lead to blood ethanol conc. of
100mg/dL
Acute ingestion Mild to Moderate
● Euphoria ● mild incoordination ● Ataxia ● Nystagmus ● impaired judgment and reflexes (that’s why we don't drink and drive bc it causes incoordination or impaired min and body coordination)
Deep intoxication
● coma ● respiratory depression ● pulmonary aspiration ● small pupils ● decreased temperature, BP and PR
Ethanol Poisoning treatment
Emergency and supportive measures; Glucose, thiamine
What CYP converts ethanol to acetaldehyde
CYP2E1
We call it the MSG poisoning ● Glutamate is the main excitatory brain neurotransmitter
Chinese Restaurant Syndrome
Burning sensation in the face, neck, and chest in sensitive individuals ● Headache, skin flushing, sweating
Chinese Restaurant Syndrome
Digoxin (Foxglove)
Lanoxin
Propranolol
Inderal
Phenylephrine In combination with
Dimetapp, Bioflu, Disudrin, Neozep, and Tuseran
Dextromethorphan
Robitussin DM also called Triple C, CCC, skittles, robo, DXM, dex, crystal dex, and DXemon juice
Lidocaine
Xylocaine
Ibuprofen
Advil
Inhibits the function of Na+/K+ - ATPase pump
Digoxin (Foxglove)
Used to treat congestive heart disease and in certain cardiac arrhythmias
Digoxin (Foxglove)
✮ NS B-adrenergic blocker
Propranolol
Directly and preferentially stimulates alpha-1 adrenergic receptors
Phenylephrine
