Also referred to as multiple-dose activated charcoal (MDAC). The technique involves continuing oral administration of activated charcoal beyond the initial dosage every 2 to 4 h. An alternative technique is to give a loading dose of activated charcoal via an orogastric tube or nasogastric tube, followed by a continuous infusion intragastrically
Serial Oral Activated Charcoal
. USE OF ANTIDOTES IN POISONING Examples include:
o Chelating Agents o Pharmaceutical Antagonist o Chemically react with biologic systems
Not only are there certain poisonings that have delayed toxicity but there are also toxins that exhibit multiple phases of toxicity. In additional, psychiatric assessment is needed especially for
suicidal patients
2 roles of the target molecule
Cell regulation and Cell maintenance
Cell regulation toxicity
Dysregulation of gene expression and Dysregulation of ongoing cell function
Cell maintenance toxicity
Impaired internal maintenance
Impaired external maintenance