Acetaminophen upon conjugation will lead to the release or the development of ()It will then be metabolized by P450 enzyme which will give the ()). The NAC react with glutathione and the NAPQI will lead to the release of sustained of () conjugates (non-toxic).
glucuronide or sulfate (non-toxic moiety). NAPQI or N-acetyl-pbenzo-quinone imine (toxic, mercapturic acid