Disposition Emergency department discharge or ICU admission • All patients with potentially serious overdose should be observed for at least ()hours before discharge or transfer to a nonmedical facility • If signs and symptoms of() develop during this time, admission for further observation and treatment is required. • Most patients admitted for poisoning or drug overdose will need observation in an (), although this depends on the potential for serious cardiorespiratory complications. • Any patient with () intent must be kept under close observation.