Prepared by M.L. Thompson, Ph. D., Dept. of General Dentistry, Tufts Dental School
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13
arrythmia
3. Verapamil is most efficacious in the treatment of
a. Atrial fibrillation
b. Atrial tachycardia
c. Ventricular tachycardia
d. Catecholamine-induced arrhythmias
(a) memorize
4. Which of the following drugs is most useful in treating or preventing
angina pectoris?
a. Digitalis
b. Quinidine
c. Propranolol
d. Procainamide
e. Pentobarbital
(c)
5. Each of the following drugs can be used in the prevention and
treatment of angina pectoris EXCEPT
a. Digitalis
b. Propranolol
c. Nitroglycerin
d. Isosorbide dinitrate
e. Pentaerythritol tetranitrate
(a)
6. All of the following drugs are useful in the treatment of hypertension
EXCEPT
a. Ephedrine
b. Reserpine
c. Methyldopa
d. Thiazide diuretics
(a)
7. Digitalis is useful in the treatment of which of the following conditions?
a. Atrial fibrillation
b. Congestive heart failure
c. Paroxysmal atrial tachycardia
d. All of the above
(d)
8. All of the following drugs are useful in the treatment of cardiac
arrhythmias EXCEPT
a. Digitalis
b. Lidocaine
c. Phenytoin
d. Procainamide
e. Aminophylline
(e)
9. The drug of choice for initial therapy for mild hypertension is
a. Reserpine
b. Guanethidine
c. Phenobarbital
d. Chlorothiazide
e. Alpha-methyldopa
(d)
10. Which of the following antihypertensives are usually reserved for
treatment of severe hypertension?
a. Sedatives and reserpine
b. Thiazide diuretics and reserpine
c. Sedatives and thiazide diuretics
d. Guanethidine and ganglionic blocking agents
(d)
11. Which of the following beta-adrenergic receptor blocking agents is
thought to be cardioselective?
a. Nadolol
b. Timolol
c. Metoprolol
d. Propranolol
(c)
Mechanism of Action Questions
Antiarrhythmics
12. Antiarrhythmic drugs, such as quinidine, suppress certain cardiac
arrhythmias by
a. Stimulating the beta-adrenergic receptor
b. Suppressing cardiac ATP-ase activity
c. Increasing ectopic pacemaker activity
d. Increasing the refractory period of cardiac muscle
(d)
13. Most drugs useful in the treatment of cardiac arrhythmias act
primarily by
a. Blocking Purkinje fibers
b. Blocking the alpha-adrenergic receptor
c. Suppressing SA node impulse formation
d. Causing a positive inotropic effect
e. Increasing the refractory period of cardiac muscle
(e)
14. The most important pharmacologic action of drugs that suppress
cardiac arrhythmias is
a. Blockade of the vagus nerve
b. Stimulation of cardiac ATP-ase activity
c. Blockade of the Beta-adrenergic receptor
d. Stimulation of the beta-adrenergic receptor
e. Increased refractory period of cardiac muscle
(e)
15. Lidocaine produces its antiarrhythmic effects by
a. Increasing AV conduction
b. Decreasing cardiac excitability
c. Increasing cardiac conduction velocity
d. Increasing spontaneous pacemaker activity
(b) arrhythmias are defined as any abnormality of the normal
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