Study Set Content:
Transamination reactions are catalyzed by specific transaminases (also called
aminotransferases
Transamination reactions are catalyzed by specific transaminases (also called aminotransferases), which require(blank) as a coenzyme
pyridoxal phosphate
alanine +
alpha-ketoglutarate
alanine + alpha-ketoglutarate enzyme
glutamate-pyruvate transaminase
alanine + alpha-ketoglutarate yields
pyruvate and glutanate
alpha-ketoglutarate +
aspartate
alpha-ketoglutarate + aspartate enzyme
glutamate-oxaloacetate transaminase
alpha-ketoglutarate + aspartate yields
oxaloacetate and glutamate
occurs when an amine group is removed from a molecule.
Deamination
The amino group (–NH2 ) is removed from an amino acid and converted to
ammonia
The amino group (–NH2 ) is removed from an amino acid and converted to ammonia, which is ultimately converted to
urea
In order for amino acids to be used in the Krebs cycle, they must first be
deaminated
Glutamate enzyme
Glutamate dehydrogenase
through this process NADP is formed into
NADPH
glutamate forms into
alpha-Iminoglutarate
alpha-Iminoglutarate enzyme
glutamate deyhydrogenase
alpha-Iminoglutarate yields
alpha-ketoglutarate
The chemical addition of a phosphate group (PO3 -) to an organic molecule
PHOSPHORYLATION
means when energy from breakdown of glucose is directly released as ATP or GTP.
Substrate level phosphorylation
In Krebs cycle, only in one step GTP is released i.e., during the conversion of
succinyl CoA
