Pepsinogen
Zymogens
Procarboxypeptidase
Zymogens
Carboxypeptidase
Active enzymes
Phospholipase
active enzyme
Phospholipase
Active enzymes
Elastase
Active enzymes
Proelastase
Zymogens
Fibrinogen
Zymogens
Fibrin
Active enzymes
regulation takes place by means of an event that occurs at a site other than the active site but that eventually affects the active site
Allosterism
ny enzyme regulated by this mechanism
allosteric enzyme:
substance that binds to the allosteric enzyme
regulator
The site to which it attaches
Regulatory site
The modification is usually a change in the primary structure, typically by addition of a functional group covalently bound to an apoenzyme (e.g. phosphorylation
Protein modification:
are enzymes that perform the same function but have different combinations of subunits and thus different quaternary structures.
Isoenzymes
dominates in the heart
H
dominates in the liver and skeletal system
M
LDH1
HHHH
LDH 2
HHHM
LDH 3
HHHM