Eicosanoids comprised of
1. Prostanoids: prostaglandins (PGs), prostacyclins (PGIs), thromboxane (TXs) 2. Leukotriene (LTs) 3. Lipoxins (LXs)
18
chained carbon
Oleic acid
C atoms are numbered from the carboxy
C (C1)
C atoms adjacent to the carboxyl C (C2, C3, C4) are known as α
β, γ respectively and the terminal
methyl (CH3 ) C is known as the
ω– or n-carbon.
Various conventions use (blank) for indicating the number and position of the double bond
∆
Exist in every mammalian tissue, acting as a local hormone
Prostaglandin
Prostaglandins Synthesized in vivo by cyclization of the center of the carbon chain of arachidonic acid to form a
cyclopentane ring
16;1;9
Palmitoleic
18;1;9
oleic
18;1;9
Elaidic
18;2;9;12
Linoleic
18;3;6,9,12
y-Linolenic
18:3;9,12,15
a-Linolenic
20:4,5,8,11,14
Arachidonic
20:5;5,8,11,14,17
Timnodonic
22:6;4,7,10,13,16,19
Cervonic
In nearly all fats
Palmitoleic
Possibly the most common fatty acid in natural fats; particularly high in olive oil
Oleic
Hydrogenated and ruminant fats
Elaidic