Study Set Content:
is the science concerned with studying the various molecules that occur in living cells and organisms and with their chemical reactions
Biochemistry
Because life depends on biochemical reactions, (blank) has become the basic language of biologic sciences
biochemistry
• A sound knowledge of (blank) is essential for the rational practice of medicine and related health sciences.
biochemistry and of other related basic disciplines
encompasses a large area of cell biology, molecular biology, and molecular genetics.
Biochemistry
overlaps biochemistry
– Related health sciences
are fundamental in illuminating the causes of diseases and in designing appropriate therapies.
Biochemical approaches
Demonstration of the nature of the genetic defects of CF
1. Reveal causes of and mechanisms of diseases
A diet low in phenylalanine for treatment of PKU
. Suggest rational treatments of diseases
Use of plasma levels in the diagnosis of MI
3. Assist in the diagnosis of diseases
Use of measurement of blood thyroxine in the neonatal diagnosis of congenital hypothyroidism
. Act as screening tests for the early diagnosis of diseases
Use of plasma enzyme alanine aminotransferase (ALT) in monitoring the progression of infectious hepatitis
Assist in the monitoring of diseases
Use of measurement of blood carcinoembryonic antigen (CEA) in patients who have been treated for colon cancer
Assist in assessing the response of diseases in therapy
The term Biochemistry is derived from Greek word whic means life
Bios
is defined as the science which deals with the chemical basis of life.
Biochemistry
It relates with the chemical constituents of living cells as well as their reactions and other processes.
Biochemistry
To explain biological structure and function in
chemical terms
To provide a complete understanding of all of the chemical processes associated with living cells at the
molecular level
To isolate the several molecules found in cells by using
salt fractionation, chromatography, electrophoresis and ultracentrifugation.
To determine the structures of several molecules by using
elemental analysis, spectroscopy, X-ray crystallography.
Biochemistry gives an idea of the constitution of the drug, its chances of degradation with varying temperature, how modification in the chemistry of medicine helps improve efficiency, and minimize side effects
Drug constituents
