Phenylalanine, tryptophan, tyrosine
Aromatic side chains
Serine and threonine
Reactive hydroxyl groups
Glycine
Hydrogen atom side chain
Glutamic and aspartic acid
Carboxylic acid side chains
Glutamine and asparagine
Amides of carboxylic acids
the only achiral amino acid; precursor of porphyrins such as heme
Glycine
are a group of heterocyclic macrocycle organic compounds composed of four modified pyrrole subunits interconnected at their alphacarbon atom via a methine bridge
Porphyrins
Tryptophan is converted to
serotonin (5- hydroxytryptamine)
• Porphyrins are a group of heterocyclic macrocycle organic compounds composed of four modified pyrrole subunits interconnected at their alphacarbon atom via a
methine bridge
is a neurotransmitter and also the precursor of melatonin
serotonin
Tryptophan to
5-Hydroxytryptophan(5-HTP)
5-Hydroxytryptophan(5-HTP) to
Serotonin
Serotonin to
N-acetylserotonin
enzyme of tryptophan tp 5-hydroxytryptophan
TPH(tryptophan decarboxylase)
enzyme of 5-hydroxytryptophan to serotonin
DDC(DOPA decarboxylase)
enzyme serotonin to n-acetylserotonin
AANAT (Aralkylamine N-acetyltransferase)
cofactor of tryptophan tp 5-hydroxytryptophan
folate
cofactor of 5-hydroxytryptophan to serotonin
vitamin B6
cofactor of serotonin to n-acetylserotonin
zinc, magnesium
N-acetylserotonin to
melatonin