Study Set Content:
Soft, easier to spread and remove than ointments
creams
Preferred in rectal and vaginal application
creams
are basically stable mixtures or oil and water phases
emulsions
what allows water and oil to be together
surfactants
aka emulsifying agents, aka emulsifiers
surfactants
by lowering the surface tension between these incompatible phases, they can interact in harmony, this would result to a homogenous preparation which we now call
emulsions
emulsions can either be
O/W OR W/O
means we suspend water molecules in oil
water-in-oil(W/O)
would feel "watery" because water is the external phase
O/W
W/O would feel
oily
Creams are generally described as
washable or non-washable.
- O/W emulsions containing large percentages of water and stearic acid or other oleaginous components
Vanishing creams -
W/O emulsion
Cold cream -
O/W emulsion
Hydrophilic ointment
When the term “cream” is used without further qualification, a (blank) is generally inferred.
water-washable formulation
semisolid systems consisting of dispersions of small or large molecules in an aqueous liquid vehicle rendered jellylike by the addition of a gelling agent.
Gels or Jellies
Gelling agent
carbomers, CMC, HPMC, tragacanth.
are high molecular weight water-soluble polymers of acrylic acid cross-linked with allyl ethers of sucrose and/ or pentaerythritol.
Carbomers
Milk of magnesia or magnesia magma
Magmas
A gel mass consisting of floccules of small distinct particles (two-phase system)
Magmas
