Gels may thicken on standing, forming a
thixotrope
Gels may thicken on standing, forming a thixotrope, and must be shaken before use to liquefy the gel and enable
pouring
contain a larger proportion of solid material (such as 25%) than ointments
pastes
solid or semisolid adhesive masses spread on a backing of paper, fabric, moleskin, or plastic
2. Plasters
plastic masses containing gelatin (15%), glycerin (40%), water (35%), and an added medicinal substance (10%)
Glycerogelatins
for varicose ulcers
Zinc gelatin
Stiffer, impenetrable
Pastes
Zinc oxide paste (Lassar's Plain Zinc Paste) -what% each of zinc oxide and starch with white petrolatum
25
miscellaneous semisolids
pastes, plasters, glycerogelatins,zinc gelatin
jars, tubes, syringes
topical
tubes, syringes
Opthalmic, nasal, vaginal, and rectal
Packaging must be tested for
stability and compatibility
Aluminum tubes are usually coated with
epoxy resin, vinyl or lacquer
Aluminum tubes are usually coated with epoxy resin, vinyl or lacquer to prevent interaction between
content and packaging
Plastic tubes
LDPE
HDPE
PP
PET
soft and resilient, good moisture barrier
LDPE
less resilient, superior moisture barrier PP
HDPE
transparent, high degree of product chemical compatibility
PET
high level of heat resistance
PP
Filling of semisolid containers
extemporaneous
direct pour into jars
large scale