Solid dosage forms usually prepared with the aid
of suitable pharmaceutical excipients.
tablets
Most tablets are used in
oral administrations
Other routes of administration:
Sublingually, Buccally, Vaginally
If tablets are NOT scored: They are NOT
intended to be
broken
May have a
special coating and/or drug
release feature
(Conventional Tablet)
Compressed tablet
They get their names from the fact that they are
tablets compressed from granules + fines
Compressed Tablet
usually they look “layered”
MULTI-PRESSED TABLET
cover up detestable taste or odor
coated tablet
enhance appearance, allow imprinting
coated tablet
The layers can
be of different
APIs
MULTI-PRESSED TABLET
Different
modes of release
Multi-pressed tablet
control the way the drug is released
Coated tablet
- protect the enclosed drug from the environment
or GI fluid
- protect “unwanted” consumer of the
drug
Coated tablet
used by men in the treatment of benign prostatic
hyperplasia
Finasteride
is absorbed by a woman who is
pregnant with a male baby, the drug has the
potential to adversely affect the developing male
fetus.
Finasteride
possibly linked to unintended use of
finasteride during early pregnancy
Aphalangia
Sugarcoated tablets coating material
Sucrose
Film-coated tablet coating material
Polymers(celluloses, cellulose acetate phtalate CAP)
Gelatin coated
gelatin