Enteric-coated
shellac, phthalates
Requires time and expertise Results to bulkier tablets
Sugarcoated
Gelcap-capsule shaped compressed tablet
Gelatin-coated
More durable less bulky, less time consuming to apply
Film-coated
Delayed-release = disintegrates in the intestines instead of stomach
Enteric-coated
bypass hepatic metabolism
SUBLINGUAL AND BUCCAL TABLETS
disc-shaped solid dosage forms containing a
medicinal agent and generally a flavoring
substance in a hard candy or sugar base.
LOZENGES OR TROCHES
enable oral absorption of acid-sensitive or poorly
absorbed (in GI) drugs Sublingual – dissolves
fast (ex. NTG) Buccal – dissolves slowly
SUBLINGUAL AND BUCCAL TABLETS
needs to be chewed or dissolve in the mouth
before swallowing
CHEWABLE TABLETS
usually doesn’t have disintegrants
Chewable tablets
compressed granular effervescent salts
EFFERVESCENT TABLETS
usually contains mannitol
CHEWABLE TABLETS
good for those who can’t swallow
Chewable tablets
assist in breaking up
the tablets and enhancing the
dissolution of the active drug
Bubble action
example: Tablet triturates
MOLDED TABLETS
soft and soluble and are designed for rapid
dissolution.
Molded tablets
mixture of lactose with or without sucrose
(5%-20%)
Diluent molded tablets
small, usually cylindrical, molded or
compressed tablets containing small amounts of usually
potent drugs.
Tablet Triturates:
combination of sucrose and lactose
Usually prepared extemporaneously/small scale/placed
inside a capsule or dissolved in liquid
Diluent tablet triturates
must be readily and completely soluble in water
Diluent