Drug
Drug to
Grind
drug- grind to
adding excipients adjuvant
Blend
drug-grind-blend to
binder solution adding liquids
agglomerate
pellet
drug-grind-blend-binder solution- granulation through coarse sieve
air or oven dry
drug-grind-blend-binder solution- granulation through coarse sieve-air or oven dry
granulation through finer sieve
drug-grind-blend-binder solution- granulation through coarse sieve-air or oven-dry-granulation through finer sieve to
lubricants
drug-grind-blend-binder solution- granulation through coarse sieve-air or oven-dry-granulation through finer sieve- lubricants
compress tablet
drug-grind-blend-binder solution- granulation through coarse sieve-air or oven-dry-granulation through finer sieve- lubricants- compress tablet
dedusting coating
dry granulation
same with wet granulation except binder solution is replaced with slugging via roller compaction, granulated through milling, and no need of drying
large flat tablet or pellets about 1 inch in diameter
slugs
direct compression
grind-add and blend adjuvants-compress
granular form of dicalcium phosphate
DI-TAB
only applicable for inherently free-flowing &
sticky materials
direct-compression
complete the rounding and smooth the tablets
smoothing and final rounding
5 types of tablet hardness tester
Stokes Monsanto-Pfizer-Strong Cobb-Schleuniger-Erweka
Example of a friabilator
Roche