Study Set Content:
Disintegrates/dissolves in the mouth within 1
minute, some within 10 sec
RAPIDLY DISINTEGRATING OR
DISSOLVING TABLETS
Allow to liquefy in the mouth before
swallowing
RAPIDLY DISINTEGRATING OR
DISSOLVING TABLETS
RAPIDLY DISINTEGRATING OR
DISSOLVING TABLETS
Methods of prep:
Lyophilization
soft
direct compression
Lyophilization*,
Excipients:
mannitol, microcrystalline cellulose,
pregelatinized starch, sodium starch glycolate,
magnesium stearate, butylated methacrylate
copolymer, crospovidone, aspartame, citric acid,
sodium bicarbonate, colloidal silicon dioxide, ferric
oxide red, and tutti-frutti flavoring.
First entry into the RDT field
Zydis Delivery System
Fastest disintegrating system on the market
Zydis Delivery System
Dissolves In The Tongue In A Few Seconds
Zydis Delivery System
LYOPHILIZATION
Foaming a mixture of
gelatin, sugar/s, drug, etc.
Foam is poured into
mold
serves as the unit dose
dispensing package
mold
Foam is lyophilized >
Packaged
Disadvantage:
Taste masking is challenging, tablet is too
soft
Also called: vaginal inserts
Vaginal tablets
tablet + solvent vehicle > sterilize* inject to the
patient
HYPODERMIC TABLETS
Uncoated, bullet shaped or ovoid tablet
Vaginal tablets
Inserted to the vagina for local effects
Vaginal tablets
Tablets with large amounts of highly potent drug
substances > further mixed with excipients to be
a suitable dose
DISPENSING OR COMPOUNDING TABLETS
used to compound prescriptions; NOT
dispensed as such to the patient
DISPENSING OR COMPOUNDING TABLETS
Contains antibacterial or antifungals
VAGINAL TABLETS
