Study Set Content:
Female reproductive organs
Animal studies demonstrate a role for (blank) and (blank)
in early reproductive processes such as ovulation,
luteolysis, and fertilization.
PGE 2 and PGF 2a
Uterine muscle contraction
PGF 2a, TXA 2, & low concentrations of PGE 2 –
cause
relaxation.
PGI 2 & high concentrations of PGE 2
is essential for the onset of
parturition.
PGF 2a & oxytocin
Despite the discovery of prostaglandins in seminal fluid,
and their uterotropic effects, the role of prostaglandins in
semen is still
conjectural
The major source of these prostaglandins is the
seminal vesicle
The major source of these prostaglandins is the seminal
vesicle; the prostate, despite the name “prostaglandin”,
and the testes synthesizes only
small amounts
The factors that regulate the concentration of
prostaglandins in human seminal plasma are not known in
detail
does promote prostaglandin
production.
testosterone
have not been found in
seminal plasma.
Thromboxane and leukotrienes
Men with a low seminal fluid concentration of
prostaglandins are relatively
infertile
is a smooth muscle-relaxing prostaglandins,
enhance penile erection by relaxing the smooth muscle of
the corpora cavernosa.
PGE 1
increases body temperature,
PGE2
PGE2 increases body temperature, predominantly via
EP
3,
although (blank) also plays a role, especially when
administered directly into the cerebral ventricles.
EP 1
Exogenous (blank) induce fever, whereas
(blank) do not.
PGF 2α and PGI2, PGD2 and TXA2
Endogenous pyrogens release
interleukin-1,
Endogenous pyrogens release interleukin-1, which in turn
promotes the synthesis and release of
PGE2.
Endogenous pyrogens release interleukin-1, which in turn
promotes the synthesis and release of PGE2. This
synthesis is blocked by
aspirin and other antipyretic
compounds.
When infused into the cerebral ventricles (blank) induces
natural sleep
PGD2
